Trimix for Erectile Dysfunction

What is Erectile Dysfunction (ED)?

ED is the inability to achieve or maintain a penile erection long enough for sexual activity. The symptoms and causes of ED can affect men at any time and can occur rarely or more frequently.

The standard of care involves a class of oral medications called PDE5 inhibitors such as Sildenafil (Viagra), Vardenafil (Levitra), and Tadalafil (Cialis) which works by relaxing the inner muscles of the penis which then results in an erection. For men who have not responded or cannot tolerate the oral options, Trimix injection is an alternative second-line medication.

What is Trimix?

Trimix is usually compounded at a Compounding Pharmacy. It is a mixture of Papaverine, Phentolamine, and Alprostadil. Trimix can be compounded at different strengths. Trimix is a safe, fast-acting, and long-lasting treatment for ED. Most Compounding Pharmacies will also ship directly to the patient. 

·Side Effects: pain during injection, painful sensation with erection, small bleeding from the injection site

·Who should Avoid Trimix: Allergy to any of the components, Medical conditions such as Sickle cell anemia, Multiple Myeloma, Leukemia, Patients who have been advised to avoid sexual activity by their doctor, history of Penile implant or deformation

You should seek immediate care at the emergency room if you experience prolonged erection or notice any redness, lumps, curvature of the erect penis, or swelling. If you have been prescribed Trimix, you may request Phenylephrine HCl 0.1% (inject 0.25ml) to be used as needed. Over-the-counter options include Icepack, Sudafed with pseudoephedrine, and Benadryl.

The content on this blog is strictly general information and not a medical recommendation. Please consult with a doctor on to discuss the best treatment option for you. 

About Author

Dr. ike ogbu

Dr. Ike Ogbu is a Board Certified Internal medicine doctor with vast experience in the treatment of acute and chronic medical conditions. He also works in the hospital setting where he manages more acute conditions. Regardless of the clinical setting, his goal every day is to provide compassionate and complete care to every patient he treats.

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